University College London

University College London

The Neuromuscular Centre at the Institute of Child Health has a longstanding tradition of excellence in the field of diagnosis, management and care of childhood neuromuscular conditions. The strength of the unit is the large critical mass of patients, the diagnostic pathology expertise together with an active program of research and key national and international collaborations.

The Neuromuscular Centre follows the largest cohort of children affected by neuromuscular conditions in UK and have an active role in networking the remaining UK Units; Francesco Muntoni is the PI in a phase I/II trial using antisense oligonucleotides in DMD in UK. The Centre has an active program of research on muscular dystrophy, which led to the identification of 5 novel genes in the last few years.

The Cochrane Neuromuscular Disease Group has been based in the MRC Centre for Neuromuscular Diseases at the Institute of Neurology, University College London since September 2008. The group aims to provide systematic reviews of all interventions for all neuromuscular diseases, including amyotrophic lateral sclerosis/motor neuron disease, peripheral nerve disorders, myasthenia gravis and neuromuscular function disorders, and of particular interest to the TREAT NMD Network, systematic reviews of interventions for muscle diseases. From our total of 82 published reviews, the group has now published 23 systematic reviews of direct relevance to TREAT NMD and has a further 11 reviews in preparation. The group’s joint co-ordinating editors are now Dr Michael Lunn and Dr Rosaline Quinlivan. Professor Richard Hughes remains on the editorial board.

Website www.neuromuscular.cochrane.org


Website www.ich.ucl.ac.uk
Website www.ucl.ac.uk

 

Francesco Muntoni Francesco Muntoni

Francesco Muntoni (Professor in Pediatric Neurology, FRCPCH, FMedSci) is Director of the Unit with oversight of both clinical and research activities.

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Juliet Ellis Juliet Ellis

Dr Juliet A. Ellis trained as a biochemist at the University of Bristol, where she developed an interest in understanding the cellular mechanisms underlying inherited diseases. However, it was her post-doctoral work at Cambridge, working with Prof Martin Bobrow of The Dept. Medical Genetics, at the university and Dr John Kendrick-Jones at Medical Research Council, Laboratory of Molecular Biology, where she was the first to identify a function of the nuclear protein emerin.

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Carol Harty

Dr Carol Harty advises on intellectual property matters and commercial activities at the Institute of Child Health.


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Richard Hughes Richard Hughes

Richard Hughes has retired after 30 years practice as consultant neurologist at Guy’s Hospital. He was the founding co-ordinating editor of the Cochrane Neuromuscular Disease Group and continues to serve on its editorial board. He serves on the Board of the Muscular Dystrophy Campaign.

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Michael Lunn Michael Lunn

Michael Lunn is a Consultant Neurologist and Clinical Lead in Neuroimmunology at the National Hospital for Neurology, London. He is the Joint Coordinating Editor of the Cochrane Neuromuscular Disease Group, a role he shares with Dr Rosaline Quinlivan. His research interests include the mechanisms and the treatment of inflammatory neuropathies.

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Rosaline Quinlivan Rosaline Quinlivan

Ros Quinlivan is a consultant in Paediatric Neuromuscular Disorders and leads transition from the Paediatric service at The Dubowitz Neuromuscular Centre to the Adult service at Queen Square. Her main interests are inherited Neuromuscular conditions (Muscular Dystrophy, SMA, congenital myopathies and metabolic muscle disease). She is a member of the Scientific Advisory Board for The Association of Glycogen Storage Disorders (AGSD UK). She is Joint Co-ordinating editor of the Cochrane Neuromuscular Disease Group with Michael Lunn

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